Benfica is having an excellent start to the season, with seven wins in as many matches in the I League and just two draws in 12 matches, one of which in their debut in the Champions League, at Dynamo Kiev (0-0).
Still recovering from the shock of Lionel Messi's departure, FC Barcelona is having a difficult start to their season, with the worst point being the 3-0 defeat at home to Bayern Munich.
The match between Benfica and FC Barcelona is scheduled for 20:00, at Estádio da Luz, in Lisbon, and will be refereed by the Italian Daniele Orsato.
In the other Group E match, Bayern Munich are looking for a second win, against Dynamo Kiev.